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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of hsa-miR-125b
ncRNA name hsa-miR-125b
ncRNA Category miRNA
Disease name uveal melanoma (UM)
Species Homo sapiens
Tissues/Cell_line cutaneous melanoma cell line G361; UM cell line OCM-113; normal human epidermal melanocytes (NHEM)
Methods microarray, qPCR
Expression pattern down-regulated
Functional description Reduction of miR-125b and upregulation of c-Jun, a main regulator of tumor progression in melanoma, were observed in malignant melanoma.
PubMed ID 24675509
Year 2014
Title Identification of microRNA expression patterns in cutaneous and uveal melanoma cell lines.
Drug-related ncRNA NO

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